INBIOMED

Publicaciones

6 años ago By mpace

​​​​​Publicaciones y Reconocimientos:

2024

  • Carniglia L, Turati J, Saba J, López Couselo F, Romero AC, Caruso C, Durand D, Lasaga M, Melanocortin-receptor 4 activation modulates proliferation and differentiation of rat postnatal hippocampal neural precursor cells, 2024, Neuropharmacology. DOI: 10.1016/j.neuropharm.2024.110058

  • Castillo AF, Poderoso C, Maloberti PM, Cornejo Maciel F, Mori Sequeiros Garcia MM, Orlando UD, Mele P, Benzo Y, Dattilo MA, Prada J, Quevedo L, Belluno M, Paz C, Podesta EJ. «Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis». J Endocrinol. 2024 Apr 4;261(2):e230391. doi: 10.1530/JOE-23-0391. PMID: 38470178.

  • Benzo Y, Prada JG, Dattilo MA, Bigi MM, Castillo AF, Mori Sequeiros Garcia MM, Poderoso C, Maloberti PM. Acyl-CoA synthetase 4 modulates mitochondrial function in breast cancer cells. Heliyon. 2024 May 3;10(9):e30639. doi: 10.1016/j.heliyon.2024.e30639. PMID: 38756582; PMCID: PMC11096749.

2023

  • Ríos Medrano MA, Bigi MM, Martínez Ponce P, Podesta EJ, Orlando UD. Exposure to anticancer drugs modulates the expression of ACSL4 and ABCG2 proteins in adrenocortical carcinoma cells. Heliyon. 2023 Oct 7;9(10):e20769. doi: 10.1016/j.heliyon.2023.e20769. PMID: 37867801; PMCID: PMC10585233.
  • New insights into signal transduction pathways in adrenal steroidogenesis: role of mitochondrial fusion, lipid mediators, and MAPK phosphatases. Mori Sequeiros Garcia MM, Paz C, Castillo AF, Benzo Y, Belluno M, Balcázar Martínez A, Maloberti PM, Cornejo Maciel F and Poderoso C. Front. Endocrinol., Volume 14 – 2023. doi: 10.3389/fendo.2023.1175677
  • Guazzone VA and Lustig L (2023), Varicocele and testicular cord torsion: immune testicular microenvironment imbalance. Front. Cell Dev. Biol. 11:1282579. doi: 10.3389/fcell.2023.1282579
  • Nicola Candia AJ, Garcia Fallit M, Peña Agudelo JA, Perez Kuper M, Gonzalez N, Moreno Ayala MA, De Simone E, Giampaoli C, Casares N, Seilicovich A, Lasarte JJ, Zanetti FA, Candolfi M. Targeting foxp3 tumor intrinsic effects using adenoviral vectors in experimental breast cancer. Viruses 2023. 15: 1813.
  • PluriBAC: A Versatile Baculovirus-Based Modular System to Express Heterologous Genes in Different Biotechnological Platforms. Amorós Morales LC, Marchesini A, Gómez Bergna SM, García Fallit M, Tongiani SE, Vásquez L, Ferrelli ML, Videla-Richardson GA, Candolfi M, Romanowski V, Pidre ML. Viruses. 2023 15: 1984.
  • Peña Agudelo JA, Pidre ML, Garcia Fallit M, Perez Kuper M, Zuccato CF, Nicola Candia AJ, Marchesini A, Vera MB, De Simone E, Giampaoli C, Amoros Morales LC, Gonzalez N, Romanowski V, Videla Richardson GA, Seilicovich A, Candolfi M. Mitochondrial peptide Humanin facilitates chemoresistance in Glioblastoma cells. Cancers 2023 15: 4061.
  • Zárate L, Miret N, Nicola Candia AJ, C. Daniel Zappia CD, Pontillo C, Florencia Chiappini F, Monczor F, Candolfi M, Randi A. Breast cancer progression and kynurenine pathway enzymes are Induced by hexachlorobenzene exposure in a HER2-positive model. Food and Chemical Toxicology. 2023 177: 113822.
  • Garcia Fallit M, Pidre ML, Asad AS, Pena Agudelo JA, Vera MB, Nicola Candia AJ, Sagripanti SB, Pérez Kuper M, Amorós Morales LC, Marchesini A, Gonzalez N, Caruso CM, Romanowski V, Seilicovich A, Videla-Richardson GA, Zanetti FA, Candolfi M. Evaluation of baculoviruses as gene therapy vectors for brain cáncer. Viruses 2023 15(3), 608
  • "Alzheimer’s disease risk after COVID-19: a view from the perspective of the infectious hypothesis of neurodegeneration". Eugenia Olivera, Albany Sáez, Lila Carniglia, Carla Caruso, Mercedes Lasaga, Daniela Durand. Neural Regeneration Research 2023. doi:10.4103
  • Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade. Conte J.G., Tellechea M.L., Park B., Ballerini M.G., Jaita G., Peluffo M.C. Front Cell Dev Biol 11:1161813, 2023. doi: 10.3389/fcell.2023.1161813.
  • "Unraveling the effect of the inflammatory microenvironment in spermatogenesis" progression. CELL AND TISSUE RESEARCH; Berlin; 2023. Ferreiro, Maria Eugenia; Méndez, Cinthia Soledad; Glienke, Leilane; Sobarzo, Cristian Marcelo; Ferraris, María Jimena; Pisera, Daniel Alberto; Lustig, Livia; Jacobo, Patricia Verónica; Theas, María Susana.
  • Smith J, Alfieri JM, Anthony N, …Pigozzi MI, … Zhou H. Fourth Report on Chicken Genes and Chromosomes 2022. Cytogenet Genome Res. 2023 Jan 30. doi: 10.1159/000529376. PMID: 36716736.

2022

  • "Angiotensin II regulates mitochondrial mTOR pathway activity dependent on acyl CoA synthetase 4 in adrenocortical cells". Katia E Helfenberger, Giuliana F Argentino, Yanina Benzo, Lucía Herrera, Paola Finocchietto, Cecilia Poderoso. Endocrinology. Oct. 2022

  • Neuroinflammation in Huntington’s disease: A starring role for astrocyte and microglia. Julieta Saba, Federico López Couselo, Julieta Bruno, Lila Carniglia, Daniela Durand, Mercedes Lasaga, Carla Caruso. Current Neuropharmacology. 2022.

  • A metabotropic glutamate receptor 3 (mGlu3R) isoform playing neurodegenerative roles in astrocytes is prematurely up‐regulated in an Alzheimerʼs model. Juan Turati, Julieta Rudi, Juan Beauquis, Lila Carniglia, Federico Lopez Couselo, Julieta Saba, Carla Caruso, Flavia Saravia, Mercedes Lasaga, Daniela Durand. Journal of Neurochemistry. 2022.

  • Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy. Mahmoud S Alghamri, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Ayman Taher, Rohit Thalla, Brandon L McClellan, Maria L Varela, Svetlana M Stamatovic, Gabriela Martinez-Revollar, Anuska V Andjelkovic, Jason V Gregory, Padma Kadiyala, Alexandra Calinescu, Jennifer A Jiménez, April A Apfelbaum, Elizabeth R Lawlor, Stephen Carney, Andrea Comba, Syed Mohd Faisal, Marcus Barissi, Marta B Edwards, Henry Appelman, Yilun Sun, Jingyao Gan, Rose Ackermann, Anna Schwendeman, Marianela Candolfi, Michael R Olin, Joerg Lahann, Pedro R Lowenstein, Maria G Castro.2022.

  • Editorial: Mitochondrial Dynamics in Endocrine Physiology and Disease. Cecilia Poderoso, Beatrice Maria Filippi, Paula Mariana Maloberti, Maria Clara Franco. Front Endocrinol (Lausanne). 2022 Feb 16;13:844842. doi: 10.3389/fendo.2022.844842. eCollection.

  • "Histone H3 Methylation and Autosomal vs. Sex Chromosome Segregation During Male Meiosis in Heteroptera. Frontiers in Ecology and Evolution"; 2022 vol. 10. Toscani, María Ayelen; Pigozzi, María Inés; Papeschi, Alba G.; Bressa, María José

  • "A BIRD´S-EYE VIEW OF CHROMOSOMES DURING MEIOTIC PROPHASE I". Basic and Applied Genetics; Buenos Aires; 2022 vol. 33 p. 1 - 15. Pigozzi, María Inés

  • "N-Acetyl cysteine improves cellular growth in respiratory-deficient yeast" BRAZILIAN JOURNAL OF MICROBIOLOGY; 2022. Sebastian P. Chapela, , Hilda I Burgos, Carlos A. Stella

  • "Synergistic Effect of Dichloroacetate and Fluconazole on the Growth of Saccharomyces cerevisiae". Journal of Pharmacology & Clinical Toxicology; 2022. Sebastian P. Chapela, Christian Congost, Manuel Alonso, Hilda I Burgos. Carlos A. Stella

  • "EDITORIAL Special Issue: The influence of biological sex in ageing". MECHANISMS OF AGEING AND DEVELOPMENT; 2022 vol. 202. Zárate, Sandra; Gredilla, Ricardo
     

 

2021

  • Relevance of angiogenesis in autoimmune testis inflammation Molecular Gualdoni G, Jacobo PV, Sobarzo CM, Pérez CV Haro Durand A, Lustig L Theas MS, Guazzone VA. Human of Reproduction. 2021 Feb 5;27(2):gaaa073. doi: 10.1093/molehr/gaaa073.

  • Dattilo M., Benzo Y., Herrera L., Prada J., Lopez P., Caruso C., Lasaga M., Garcia C., Paz C., Maloberti P. “Regulation and role of Acyl-CoA synthetase 4 in glial cells”. J Steroid Biochem Mol Biol 2021, 208:105792. doi: 10.1016/j.jsbmb.2020.105792.

  • Mitochondrial humanin peptide acts as a cytoprotective factor in granulosa cell survival. Reproduction. Marvaldi, C; Martin, D; Conte JG, Gottardo, MF; Pidre, M; Imsen, M; Irizarri M, Manuel S; Duncan, F; Romanowski, V; Seilicovich, A; Jaita, G. Reproduction. Reproduction 2021 Mar 1; REP-20-0197.R3. doi: 10.1530/REP-20-0197. Online ahead of print.

  • Relevance of angiogenesis in autoimmune testis inflammation. Gualdoni GS, Jacobo PV, Sobarzo CM, Pérez CV, Durand LAH, Theas MS, Lustig L, Guazzone VA. Mol Hum Reprod. 27(2): gaaa073. doi: 10.1093/molehr/gaaa073. 2021

  • "New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis” Castillo AF*, Orlando U*, Maloberti PM*, Prada J, Dattilo MA, Solano A, Bigi MM, Ríos Medrano M, Torres MT, Indo S, Caroca G, Contreras HR, Marelli BE, Salinas FJ, Salvetti N, Ortega HH, Lorenzano Menna P, Szajnman S, Gomez DE, Rodríguez JB and Podesta EJ. Cell Mol Life Sci. 2021 Mar;78(6):2893-2910. DOI: 10.1007/s00018-020-03679-5. *contributed equally.

  • Gonzalez N, Asad AS, Gómez Escalante J, Peña Agudelo JA, Nicola Candia AJ, García Fallit M, Seilicovich A, Candolfi M. Potential of IDH mutations as immunotherapeutic targets in gliomas: a review and meta-analysis. Expert Opin Ther Targets. 2021 12: 1045-1060

  • Asad AS, Candia AJN, González N, Zuccato CF, Seilicovich A, Candolfi M. Current Non-Viral Gene Therapy Strategies for the Treatment of Glioblastoma. Curr Med Chem. 2021. 10.3389.

  • Garcia-Fabiani MB, Haase S, Comba A, Carney S, McClellan B, Banerjee K, Alghamri MS, Syed F, Kadiyala P, Nunez FJ, Candolfi M, Asad A, Gonzalez N, Aikins ME, Schwendeman A, Moon JJ, Lowenstein PR, Castro MG. Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies. Front Oncol. 2021 11: 631037.

  • Banerjee K, Núñez FJ, Haase S, McClellan BL, Faisal SM, Carney SV, Yu J, Alghamri MS, Asad AS, Candia AJN, Varela ML, Candolfi M, Lowenstein PR, Castro MG. Current Approaches for Glioma Gene Therapy and Virotherapy. Front Mol Neurosci. 2021. 14: 621831.

  • "The COVID-19 pandemic and its global effects on dental practice. An International survey." JOURNAL OF DENTISTRY; 2021. Mendez, C.F.

  • "DNA Organization along Pachytene Chromosome Axes and Its Relationship with Crossover Frequencies". INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Año: 2021 vol. 22. Del Priore, Lucía; Pigozzi, María Inés.

  • "Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina" Cancers; Lugar: Basel; 2021 vol. 13. Angela R. Solano, Pablo G. Mele, Fernanda S. Jalil, Natalia C. Liria, Ernesto J. Podestá, Leandro G. Gutiérrez.

  • "N-acetylcysteine increases creatinine levels without lowering reactive oxygen species levels" Fronteras en Medicina; 2021. Sebastian P. Chapela, Hilda I. Burgos, Alexis Muryan, María C. Ricart, Manuel Alonso, Carlos A. Stella

  • "Design to Purify Environments of Microorganisms: Prospects For The Emergence of Covid19" International Journal of Scientific Engineering and Applied Science; 2021. Isabel Camacho, Hilda I. Burgos, Sebastian P. Chapela, Carlos A. Stella

  • "Long-Lasting Changes in Glial Cells Isolated From Rats Subjected to the Valproic Acid Model of Autism Spectrum Disorder"Frontiers in Pharmacology; 2021 vol. 12. Traetta, Marianela; Uccelli, Nonthué; Zárate, Sandra; Gómez Cuautle, Dante; Ramos, Alberto; Reinés, Analía

  • "Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders". Molecular Autism; 2021 vol. 12.  Traetta, Marianela; Codagnone, Martín; Uccelli, Nonthué; Ramos, Alberto; Zárate, Sandra; Reinés, Analía

2020

  • PATENTE:
    PCT “Acyl-CoA synthetase 4 (ACSL4) inhibitory compound” Podesta EJ, Gomez D, Rodríguez JB, Lorenzano Menna P, Orlando UD, Maloberti PM, Castillo AF, Solano AR, Szajnman SH, Prada J. International Bureau of the World Intellectual Property OrganizationSolicitud: 20/02/2020 - PCT/IB2020/051433.Publicación: 27/08/2020 - International Publication Number: WO/2020/170192

  • Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord. Diego Moreno, Cristian M Sobarzo, Livia Lustig, Marcelo G Rodríguez Peña, Vanesa Anabella Guazzone. Asian Journal of Andrology 22: 112-117. 2020. http://doi.org/10.4103/aja.aja_30_19

  • Pathomechanisms of autoimmune based testicular inflammation. Lustig, Livia; Guazzone V; Theas M S; Pleuger C; Jacobo P V,; Perez CV; Fikak M; Meinhardt A. Frontiers Immunology; Año: 2020

  • Immune cell subtypes and their function in the testis. Busham S; Theas MS; Guazzone V; Jacobo P V,; Wang Min; Fijak, M; Meinhardt A; Lustig L. Frontiers in Immunology; Año: 2020

  • Relevance of angiogenesis in autoimmune testis inflammation. Gualdoni G; Pérez C V, Sobarzo C M, Jacobo P V, Theas M S, Denduchis B, Lustig L; Sobarzo Cristian Marcelo; Haro Durand, L A; Guazzone V A. Molecular human reproduction, Oxford; Año: 2020

  • C-C motif chemokine receptor 2 as a novel intermediate in the ovulatory cascade. Jaworski JP, Urrutia M, Dascal E, Jaita G, Peluffo MC. Mol Hum Reprod. 2020 May 15;26(5):289-300. doi: 10.1093/molehr/gaaa020. 

  • J. Turati, D. Ramírez, L. Carniglia, J. Saba, C. Caruso, J. Quarleri, D. Durand, M. Lasaga,. “Antioxidant and neuroprotective effects of mGlu3 receptor activation on astrocytes aged in vitro”. Neurochem Int. 2020, 140:104837. doi: 10.1016/j.neuint.2020.104837.

  • J. Saba, F. López Couselo, J. Turati, L. Carniglia, D. Durand, A. de Laurentiis, M. Lasaga, C. Caruso. “Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin”. J Neuroinflammation 2020, 17:290 doi: 10.1186/s12974-020-01965-4.

  • Asad AS, Nicola Candia AJ, Gonzalez N, Zuccato CF, Seilicovich A, M Candolfi, The role of the prolactin receptor pathway in the pathogenesis of glioblastoma: What do we know so far? Invited review Expert Opinion on Therapeutic Targets 2020 24: 1121-1133.

  • Moreno Ayala MA, Gottardo MF, Zuccato CF, Pidre ML, Nicola Candia AJ, Asad AS, Imsen M, Romanowski V, Seilicovich A, Candolfi M. Humanin promotes tumor progression in experimental triple negative breast cancer. Scientific Reports 2020 10: 8542. doi: 10.1038/s41598-020-65381-7

  • Garcia-Fabiani MB, Ventosa M, Comba A, Candolfi M, Nicola Candia AJ, Alghamri M, Kadiyala P, Carney S, Faisal SM, Schwendeman A, Moon JJ, Scheetz L, Lahann J, Mauser A, Lowenstein PR, Castro MG. Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development. Expert Opin Investig Drugs. 2020. 4:1-26. doi: 10.1080/13543784.2020.1768528.

  • Altshuler DB, Kadiyala P, Nuñez FJ, Nuñez FM, Carney S, Alghamri MS, Garcia-Fabiani MB, Asad AS, Nicola Candia AJ, Candolfi M, Lahann J, Moon JJ, Schwendeman A, Lowenstein PR, Castro MG. Prospects of biological and synthetic pharmacotherapies for glioblastoma. Expert Opin Biol Ther. 2020. 20: 305-317.

  • MAP KINASE PHOSPHATASE-3 IS INVOLVED IN P21 INDUCTION BY ANGIOTENSIN II IN HUMAN ADRENOCORTICAL H295R CELLS. Mori Sequeiros Garcia MM, Cohen Sabban JM, Mele PG, Nudler SI, Mendez CF, Maloberti PM and Paz C. Heliyon . 2020 Mar 10;6(3):e03519.

  • "MLH1 focus mapping in the guinea fowl (Numida meleagris) give insights into the crossover landscapes in birds". PLOS ONE; 2020 vol. 15. Del Priore, Lucía; Pigozzi, María Inés

  • "Anterior Pituitary gland synthesizes Dopamine from L‐3,4‐dihydroxyphenylalanine (L‐Dopa)". JOURNAL OF NEUROENDOCRINOLOGY.; 2020. Orrillo, Santiago Jordi; de Dios, Nataly; Asad, Antonela Sofía; de Fino, Fernanda; Imsen, Mercedes; Romero, Ana Clara; Zárate, Sandra; Ferraris, Jimena; Pisera, Daniel.

  • "Serum reactive oxygen species and apoptosis markers in septic patients" Anaesthesiol Intensive Ther; 2020. Sebastian Chapela, Isabel Burgos, Amalia Schiel, Manuel Alonoso, Carlos Stella.
     

2019

  • Association between high-fat diet feeding and male fertility in high reproductive performance mice. Gómez-Elías MD, Rainero Cáceres TS, Giaccagli MM, Guazzone VA, Dalton GN, De Siervi A, Cuasnicú PS, Cohen DJ, Da Ros VG. Sci. Rep. 9: 18546. doi: 10.1038/s41598-019-54799-3. 2019.

  • Role of indoleamine 2,3-dioxygenase in testicular immune-privilege. Gualdoni G. S., Jacobo P. V., Sobarzo C. M., Pérez C. V., Matzkin M. E., Höcht C., Frungieri M., Hill M., Anegon I., Lustig L., Guazzone V. A. Sci. Rep. 9(1):15919. doi: 10.1038/s41598-019-52192-8. 2019.

  • The inflammatory mediators TNFalpha; and nitric oxide arrest spermatogonia B GC-1 cell cycle. Ferreiro, Maria Eugenia; Cinthia Soledad Méndez; González Lucas; Amarilla, María Sofía; Jacobo Patricia Verónica; Sobarzo Cristian Marcelo; Theas María Susana. Reproductive Biology; Año: 2019

  • Asad AS, Nicola Candia AJ, Gonzalez N, Zuccato CF, Abt A, Orrillo SJ, Lastra Y, De Simone E, Boutillon F, Goffin V, Seilicovich A, Pisera DA, Ferraris MJ, Candolfi M. Prolactin and its receptor as therapeutic targets in glioblastoma Scientific Reports 2019 9: 19578.

  • Gori S, Alcain J, Vanzulli S, Moreno Ayala MA, Candolfi M, Jancic C, Geffner J, Vermeulen M, Salamone G. Acetylcholine-treated murine dendritic cells promote inflammatory lung injury. PLoS One. 2019 14: e0212911.

  • Zuccato CF, Asad AS, Nicola Candia AJ, Gottardo MF, Moreno Ayala MA, Theas MS, Seilicovich A, Candolfi M. Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases. Invited Review. Expert Opinion on Therapeutic Targets. 2019 23: 117-126.

  • J. Saba, L. Carniglia, D. Ramírez, J. Turati, M. Imsen, D. Durand, M. Lasaga, C. Caruso. “Melanocortin 4 receptor activation protects striatal neurons and glial cells from 3-nitropropionic acid toxicity” Mol Cell Neurosci 2019, 94:41-51. doi 10.1016/j.mcn.2018.12.002.

  • D. Ramírez, J. Saba, J. Turati, L. Carniglia, D. Durand, C. Caruso, M. Lasaga. “NDP-MSH reduces oxidative damage induced by palmitic acid in primary astrocytes” J Neuroendocrinol 2019 Feb 3:e12673. doi: 10.1111/jne.12673.

  • D. Durand, Turati, M.J. Rudi, D. Ramírez, L. Carniglia, J. Saba, C. Caruso, von Bernhardi R., M. Lasaga “Unraveling the b–amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPa, and class-A scavenger receptor”. Neurochem Int. 2019 131:104547. doi: 10.1016/j.neuint.2019.104547

  • Sciurano RB, Pigozzi MI, Benavente R. Disassembly of the synaptonemal complex in chicken oocytes analyzed by super-resolution microscopy. Chromosoma. doi:10.1007/s00412-019-00693-w. PubMed PMID: 30793238

  • Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells. Katia E. Helfenberger, Ana F. Castillo, Pablo G. Mele, Ana Fiore, Lucía Herrera, Paola Finocchietto, Ernesto J. Podestá; Cecilia Poderoso. J Steroid Biochem Mol Biol. Jun 13 (2019);192:105413. doi: 10.1016/j.jsbmb.2019.105413. 

  • The effect of Nitric Oxide on mitochondrial respiration. Juan José Poderoso, Katia E. Helfenberger, Cecilia Poderoso. Nitric Oxide. Jul 1 (2019); 88: 61-72. doi: 10.1016/j.niox.2019.04.005.

  • “Autoimmune orchitis and autoimmune oophoritis”. L. Lustig, V.A.Guazzone, K.S.K. Tung. Capítulo del libro: “The Autoimmune Diseases”. 6a. edición. N. Rose and I. R. Mackay, eds. Elsevier/Academic Press, en prensa, 2019. isbn 978-0-12-384929-8

  • Camilletti MA, Abeledo Machado AI, Pérez PA, Faraoni EY, De Fino F, Rulli SB, Ferraris J, Pisera D, Gutiérrez S, Thomas P, Diaz-Torga G. mPRs represent a novel target for PRL inhibition in experimental prolactinomas. Endocr Relat Cancer. 2019 Mar 1. pii: ERC-18-0409.R2. doi: 10.1530/ERC-18-0409. [Epub ahead of print]

  • de Dios N, Orrillo SJ, Irizarri M, Theas M, Boutillon F, Candolfi M, Seilicovich A, Goffin V, Pisera D, Ferraris J. JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes. Neuroendocrinology. 2019;108(2):84-97. doi: 10.1159/000494975.

  • Camilletti MA, Abeledo Machado AI, Ferraris J, Pérez PA, Faraoni EY, Pisera D, Gutiérrez S, Diaz-Torga G. Role of GPER in the anterior pituitary gland focusing on lactotroph function. J Endocrinol. 2019 Feb 1;240(2):99-110. doi: 10.1530/JOE-18-0402.

  • “Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells” Dattilo MA, Benzo Y, Herrera LM, Prada JG, Castillo AF, Orlando UD, Podesta EJ, Maloberti PM. Sci Rep. 2019 Jul 16;9(1):10324. DOI: 10.1038/s41598-019-46776-7.

  • "Determinación de la concentración de NaCl para el tratamiento de edema cerebral." Journal of Biochemistry Education; San Pablo; 2019. Stella C.A.

  • "Humanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons". Frontiers in Aging Neuroscience; 2019 vol. 11. Zárate Sandra; Traetta, Marianela; Codagnone, Martín; Seilicovich, Adriana; Reinés, Analía
     

2018

  • PATENTE:
    PCT “Compositions And Methods For Inhibiting Growth of ACSL4-overexpressing Tumors” Podesta EJ, Castillo AF, Orlando UD, Maloberti PM, Solano AR.International Bureau of the World Intellectual Property Organization Solicitud: 03/11/2017 - International Application Number: PCT/IB2017/056879 Publicación: 17/05/2018 - International Publication Number: WO2018087641A1

  • Camilletti MA, Ferraris J, Abeledo-Machado A, Converse A, Faraoni E, Pisera D, Gutierrez S, Thomas P, Díaz-Torga G. Participation of membrane progesterone receptor α in the inhibitory effect of progesterone on prolactin secretion. . J Neuroendocrinol. 2018 Sep;30(9):e12614. doi: 10.1111/jne.12614.

  • "Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4". Carvajal G, Brukman NG, Weigel Muñoz M, Battistone MA, Guazzone VA, Ikawa M, Haruhiko M, Lustig L, Breton S, Cuasnicu PS. Sci Rep. 8(1): 17531. doi: 10.1038/s41598-018-35719-3. 2018.

  • Guest Editors Foreword. Livia. Lustig, Jean-.Pierre Allam. Suppl. ANDROLOGIA “Current concepts in inflammatory disorders in male infertility”, V50 (issue 11) doi: 10.1111/and.13186 , 2018.

  • Nielsen SM et al. Genetic Testing and Clinical Management Practices for Variants in Non-BRCA1/2 Breast (and Breast and Ovarian) Cancer Susceptibility Genes: an International Survey by the ENIGMA Clinical Working Group,"  Journal of Clinical Oncology Precision Oncology, in press, 2018.  Coautora Solano AR.

  • From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America, Mini Review in "Cancer Genetics and Epigenetics" of the International Journal of Cancer, in press, 2018. Coautora Solano AR.

  • Acyl-CoA Synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression. Ulises D Orlando, Ph.D; Ana F Castillo, Ph.D; Mayra A Ríos Medrano, Technician; Angela R Solano, Ph.D; Paula M Maloberti, Ph.D; Ernesto J Podestá, Prof. Ph.D. Biochemical Pharmacology 2018. in press.

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. Rebbeck TR, Friebel TM, Friedman E, Hamann U, Huo D, Kwong A, Olah E, Olopade OI, Solano AR, Teo SH, Thomassen M, Weitzel JN, Chan TL, Couch FJ, Goldgar DE, Kruse TA, Palmero EI, Park SK, Torres D, van Rensburg EJ, McGuffog L, Parsons MT, Leslie G, Aalfs CM, Abugattas J, Adlard J, Agata S, Aittomäki K, Andrews L, Andrulis IL, Arason A, Arnold N, Arun BK, Asseryanis E, Auerbach L, Azzollini J, Balmaña J, Barile M, Barkardottir RB, Barrowdale D, Benitez J, Berger A, Berger R, Blanco AM, Blazer KR, Blok MJ, Bonadona V, Bonanni B, Bradbury AR, Brewer C, Buecher B, Buys SS, Caldes T, Caliebe A, Caligo MA, Campbell I, Caputo SM, Chiquette J, Chung WK, Claes KBM, Collée JM, Cook J, Davidson R, de la Hoya M, De Leeneer K, de Pauw A, Delnatte C, Diez O, Ding YC, Ditsch N, Domchek SM, Dorfling CM, Velazquez C, Dworniczak B, Eason J, Easton DF, Eeles R, Ehrencrona H, Ejlertsen B; EMBRACE, Engel C, Engert S, Evans DG, Faivre L, Feliubadaló L, Ferrer SF, Foretova L, Fowler J, Frost D, Galvão HCR, Ganz PA, Garber J, Gauthier-Villars M, Gehrig A; GEMO Study Collaborators, Gerdes AM, Gesta P, Giannini G, Giraud S, Glendon G, Godwin AK, Greene MH, Gronwald J, Gutierrez-Barrera A, Hahnen E, Hauke J; HEBON, Henderson A, Hentschel J, Hogervorst FBL, Honisch E, Imyanitov EN, Isaacs C, Izatt L, Izquierdo A, Jakubowska A, James P, Janavicius R, Jensen UB, John EM, Vijai J, Kaczmarek K, Karlan BY, Kast K, Investigators K, Kim SW, Konstantopoulou I, Korach J, Laitman Y, Lasa A, Lasset C, Lázaro C, Lee A, Lee MH, Lester J, Lesueur F, Liljegren A, Lindor NM, Longy M, Loud JT, Lu KH, Lubinski J, Machackova E, Manoukian S, Mari V, Martínez-Bouzas C, Matrai Z, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Mensenkamp AR, Mickys U, Miller A, Montagna M, Moysich KB, Mulligan AM, Musinsky J, Neuhausen SL, Nevanlinna H, Ngeow J, Nguyen HP, Niederacher D, Nielsen HR, Nielsen FC, Nussbaum RL, Offit K, Öfverholm A, Ong KR, Osorio A, Papi L, Papp J, Pasini B, Pedersen IS, Peixoto A, Peruga N, Peterlongo P, Pohl E, Pradhan N, Prajzendanc K, Prieur F, Pujol P, Radice P, Ramus SJ, Rantala J, Rashid MU, Rhiem K, Robson M, Rodriguez GC, Rogers MT, Rudaitis V, Schmidt AY, Schmutzler RK, Senter L, Shah PD, Sharma P, Side LE, Simard J, Singer CF, Skytte AB, Slavin TP, Snape K, Sobol H, Southey M, Steele L, Steinemann D, Sukiennicki G, Sutter C, Szabo CI, Tan YY, Teixeira MR, Terry MB, Teulé A, Thomas A, Thull DL, Tischkowitz M, Tognazzo S, Toland AE, Topka S, Trainer AH, Tung N, van Asperen CJ, van der Hout AH, van der Kolk LE, van der Luijt RB, Van Heetvelde M, Varesco L, Varon-Mateeva R, Vega A, Villarreal-Garza C, von Wachenfeldt A, Walker L, Wang-Gohrke S, Wappenschmidt B, Weber BHF, Yannoukakos D, Yoon SY, Zanzottera C, Zidan J, Zorn KK, Hutten Selkirk CG, Hulick PJ, Chenevix-Trench G, Spurdle AB, Antoniou AC, Nathanson KL. Hum Mutat. 2018 May;39(5):593-620. doi: 10.1002/humu.23406. Epub 2018 Mar 12.

  • BRCA1 and BRCA2 mutation other than the founder alleles amount Ashkenazi Jewish in the population of Argentina. Angela R Solano, Natalia C Lirial, Fernanda S Jalil, Daniela M Faggionato, Pablo G Mele, Alejandra ,Mampel, Florencia Cardosoand, Ernesto J Podesta. Frontiers in Oncology, August 21th, 2018.

  • BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population. Cardoso FC, Goncalves S, Mele PG, Liria NC, Sganga L, DiazPerez I, Podesta EJ, Solano AR. HumGenomics. 2018 Aug 13;12(1):39. doi: 10.1186/s40246-018-0171-5.

  • Inflammation and spermatogenesis. M. S. Theas, P. Jacobo, Pérez C.,V. A. Guazzone, L. Lustig. “Spermatogenesis: Biological and Clinical Implications”. Editado por C. Yan Cheng. CRC Press Editorial. Taylor & Francis Group. 2018.

  • C. Caruso.HD 2018 1er premio Investigación sobre Enfermedad de Huntington en Argentina- Fundación HD Lorena Scarafiocca. En búsqueda de nuevos blancos terapeuticos para la enfermedad de Huntington.

  • J. Saba, J. Turati, D. Ramírez, L. Carniglia, D. Durand, M. Lasaga, C. Caruso. “Astrocytes truncated-TrkB mediates BDNF antiapoptotic effect leading to neuroprotection”. J Neurochem 2018, doi 10.1111/jnc.14476.

  • Kamran N, Alghamri MS, Nunez FJ, Shah D, Asad AS, Candolfi M, Altshuler D, Lowenstein PR, Castro MG.  Current state and future prospects of immunotherapy for glioma. Immunotherapy 2018 10:317-339.

  • Gottardo MF, Pidre ML, Zuccato C, Asad AS, Imsen M, Jaita G, Candolfi M, Romanowski V, Seilicovich A. Baculovirus-based gene silencing of Humanin for the treatment of pituitary tumors. Apoptosis 2018 23: 143-151. doi: 10.1007/s10495-018-1444-0.

  • Guazzone V. A.. Exploring the Role of Antigen presenting cells in Male Genital Tract. Andrologia.: Wiley Online Library. 2018 vol. n°. p - . . eissn 1439-0272

  • Surkin PN, Brenhouse H, Deak T, Liberman AC, Lasaga M.Stress, alcohol and infection during early development: a brief review of common outcomes and mechanisms.J Neuroendocrinol. 2018 Apr 22:e1260 doi: 10.1111/jne.12602. [Epub ahead of print] Review

  • Deficiency of Fibroblast Growth Factor 2 (FGF-2) leads to abnormal spermato- genesis and altered  sperm physiology.  Saucedo L,   Rumpel R,  Sobarzo C,  Schreiner D,  Brandes G, Lustig  L, Vazquez-Levin MH, Grothe  C, Marín-Briggiler C.  J Cell Physiology, 2018, doi0.1002/jcp26876.

  • Involvement of Fibroblast Growth Factor 2 (FGF2) and its receptors in the regulation of mouse sperm physiology. Lucía Saucedo, Regina Rumpel, Cristian Sobarzo, Dietmar , Schreiner, Gudrun Brandes, Livia Lustig, Mónica Hebe Vazquez-Levin, Claudia Grothe, Clara Marín-Briggiler. Reproduction, Junio 2018, doi:10.1530/REP-18-0133

  • "ACSL4” P Maloberti*, AF Castillo*, UD Orlando, EJ Podestá. (*contributed equally to this work). Encyclopedia of Signaling Molecules, 2nd Edition. Pág. 1-8. Editor: Sangdun Choi. Research. Editorial: Springer, New York. Plataforma: Meteor. (2018) ISBN: 978-3-319-67198-7. DOI: https://doi.org/10.1007/978-3-319-67199-4_101897

  • Chapter: “StAR”. Cecilia Poderoso; Ana F. Castillo, Pablo G. Mele, Paula Maloberti, Ernesto J. Podestá. Encyclopedia of Signaling Molecules, 2nd Edition. Editor: Sangdun Choi. Editorial: Springer, New York. Plataforma: Meteor. p: 5161-5169 (2018).

  • Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells”. Helfenberger K, Villalba N, Buchholz B, Boveris A, Poderoso JJ, Gelpi RJ, Poderoso C. (2018) PLoS One. Feb 28;13(2):e0193022. doi: 10.1371/journal.pone.0193022. 

  • Germ cell apoptosis and survival in testicular inflammation. MS Theas. Andrologia, in the “Special issue on inflammation”. En prensa, 2018.

  • JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes, Neuroendocrinology. Nataly de Dios, Santiago Orrillo, Martín Irizarri, Florencia Gottardo, María Susana Theas, Florence Boutillon, Marianela Candolfi, Adriana Seilicovich Vincent Goffin, Daniel Pisera, Jimena Ferraris. En prensa, 2018.

  • Juan Turati. Beca otorgada por la International Brain Research Organization (IBRO) para asistir al  11th FENs Forum of Neuroscience (Berlin, Alemania), 2018.

  • Pérez Millán MI, Vishnopolska SA, Daly AZ, Bustamante JP, Seilicovich A, Bergadá I, Braslavsky D, Keselman AC, Lemons RM, Mortensen AH, Marti MA, Camper SA, Kitzman JO. Next generation sequencing panel based on single molecule molecular inversion probes for detecting genetic variants in children with hypopituitarism. Mol Genet Genomic Med. 2018 May 8. doi: 10.1002/mgg3.395.

  • Self-medication in patients seeking care in a dental emergency service. Acta Odontologica Latinoamericana: AOL.; Buenos Aires; 2018 vol. 31 p. 117 - 121. Stolbizer, F.; Roscher, D.F.; Andrada, M.M.; Faes, L.; Arias, C.; Siragusa, C.; Prada, S.; Saiegh, J.; Rodriguez, D.; Gualtieri, A.; Mendez, C.F.

  • "Parenteral Succinate Reduces Systemic ROS Production in Septic Rats, but It Does Not Reduce Creatinine Levels", OXIDATIVE MEDICINE AND CELLULAR LONGEVITY;  Austin, Texas; 2018 vol. 2018 p. 1 - 6. Chapela S., Congost, C., Canzonieri R., Muryan A., Alonso M., Stella C.

2017

  • PATENTE:
    Registro: US 9737515 B2. Otorgado. Aprobada EEUU 4/2017. "COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF ACSL4-OVEREXPRESSING TUMORS". Podesta, Ernesto J.; Castillo, Ana F.; Orlando, Ulises; Maloberti, Paula; Solano, Angela. CONICET.
  • L. Carniglia L, D. Ramírez,  D. Durand, J. Saba, J. Turati, C. Caruso, Scimonelli TN, Lasaga M. Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Disease. Mediators Inflamm 2017:5048616.
     
  • D. Durand, L. Carniglia, J. Turati, D. Ramírez, J. Saba, C. Caruso, M. Lasaga. Amyloid-beta neurotoxicity and clearance are both regulated by glial group II metabotropic glutamate receptors. Neuropharmacology 2017, 123:274-286
     
  • Moreno Ayala MA, Gottardo MF, Gori MS, Nicola Candia AJ, Caruso C, De Laurentiis A, Imsen M, Klein S, Bal de Kier Joffé E, Salamone G, Castro MG, Seilicovich A, Candolfi M. Dual activation of Toll-like receptors 7 and 9 impairs the efficacy of antitumor vaccines in murine models of metastatic breast cancer. J Cancer Res Clin Oncol. 2017, 143 (9): 1713-1732.
     
  • Zárate S, Astiz M, Magnani N, Imsen M, Merino F, Alvarez S, Reines A, Seilicovich A. Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus. J Endocrinol. 2017  Apr;23 3(1):1-14. doi: 10.1530/JOE-16-0451. 
     
  • Zárate S, Stevnsner T, Gredilla R. Role of Estrogen and Other Sex Hormones in Brain Aging. Neuroprotection and DNA Repair. Front. Aging Neurosci. 9:430, 2017. doi: 10.3389/fnagi.2017.00430.
     
  • Chandran M, Candolfi M, Shah D, Mineharu Y, Yadav VN, Koschmann C, Asad AS, Lowenstein PR, Castro MG. Single vs. combination immunotherapeutic strategies for glioma. Expert Opinion oBiological Therapy 2017 17:543-554.n
     
  • Kamran N, Kadiyala P, Saxena M, Candolfi M, Li Y, Moreno Ayala MA, Raja N, Shah D, Lowenstein PR, Castro MG. Immunosuppressive myeloid cells' blockade in the glioma microenvironment enhances the efficacy of immune stimulatory gene therapy. Molecular Therapy2017 25: 232-248.
     
  • Gottardo MF, Moreno Ayala MA, Zárate S, Ferraris J, Pisera D, Candolfi M, Jaita G, Seilicovich A. Humanin inhibits apoptosis in pituitary tumor cells through several signaling pathways including NF-κB activation Journal Cell Commun Signaling 2017 Dec;11(4):329-340. doi: 10.1007/s12079-017-0388-4. Epub 2017 Apr 4.
     
  • Asad AS, Moreno Ayala MA, Gottardo MF, Zuccato C, Nicola Candia A, Zanetti FA, Seilicovich A, Candolfi M.  Viral gene therapy for breast cancer: Progress and challenges. Expert Opin Biol Ther. 2017 Aug;17(8):945-959. doi: 10.1080/14712598.2017.1338684. Epub 2017 Jun 12.
     
  • Moreno Ayala MA, Gottardo MF, Imsen M, Asad AS, Bal de Kier Joffé E, Casares N, Lasarte JJ, Seilicovich A, Candolfi M. Therapeutic blockade of Foxp3 in experimental breast cancer models. Breast Cancer Res Treat. 2017 Nov;166(2):393-405. doi: 10.1007/s10549-017-4414-2. Epub 2017 Jul 29.
     
  • Moreno Ayala MA, Gottardo MF, Asad AS, Zuccato C, Nicola Candia A, Seilicovich A, Candolfi M. Immunotherapy for the treatment of breast cancer. Expert Opin Biol Ther. 2017 Jul;17(7):797-812. doi: 10.1080/14712598.2017.132456 Epub 2017 May 8. 
     
  • Machado I, Schioth HB, Lasaga M, Scimonelli T, IL-1 beta reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects.Neuropharmacology. 2018, 128:314-323. doi: 10.1016/j neuropharm.2017.09.041. Epub 2017 Oct 14.
     
  • Suares Alejandra; Mori Sequeiros García María Mercedes; Paz Cristina; Gonzalez-Pardo Verónica. Antiproliferative effects of Bortezomib in endothelial cells transformed by viral G protein-coupled receptor associated to Kaposi's sarcoma. Cellular Signalling; Lugar: Amsterdam; Año: 2017 vol. 32 p. 124 - 132
     
  • Broad-scale recombination pattern in the primitive bird Rhea americana (Ratites, Palaeognathae). del Priore L, Pigozzi MI. PLoS One. 2017 Nov 2;12(11):e0187549. doi: 10.1371/journal.pone.0187549.
     
  • Delia Ramírez. Beca otorgada por la International Brain Research Organization (IBRO) para asistir al XIII European Meeting on Glial Cells in Health and Disease (Edimburgo, Reino Unido), 2017.
  • Henry Knowles Beecher: Ciudadano, profesional e investigador. Un camino hacia la integridad. Revista Redbioética/UNESCO; Montevideo; 2017 vol. 2 p. 23 - 31. Mendez, C.F.; Cardozo de Martinez, C.A.; Actis, A.; Andreau de Bennato, M.; Benites Estupiñan, E.M.; Cudeiro, P.; Duro, E.A.; Garau, M.L.; Gubert, I.C.; López Dávila, L.M.; Mainetti, J.L.; Quiroz Malca, E.; Sotomayor Saavedra, M.A.; Torres, F.A.; Valeria Monge, C.J.; Sorokin, P.
  • "Los pacientes sépticos en terapia intensiva no tienen mayores niveles sistémicos de especies reactivas de oxígeno (ROS) que los voluntarios sanos" Revista Argentina de Medicina; 2017 vol. 5 p. 213 - 219. Sebastian P. Chapela, Isabel Burgos, Florencia M. Ballestero, María S. Raña, Florencia Lascar, Santiago Sac, Pablo Lucero, Emiliano J. Descotte, Elías D. Soloaga, Miguel A. Blasco, Manuel Alonso, Carlos A. Stella.
  • "The Research Strategy Needs to Dialogue with the Science Student". Journal of Basic and Applied Scientific Research; Cairo; 2017 vol. 7 p. 21 - 24. Christian Congost, Sebastian Chapela, Manuel Alonso, Hilda Burgos, Carlos A. Stella.

2016

  • Valentich MA, Zárate S, Jaita G, Seilicovich A. Glándulas endocrinas. En: Histología y Embriología del ser humano: Bases celulares y moleculares. 5ª edición, ed. A. Eynard, M.A. Valentich y R.A.Rovasio, Editorial Médica Panamericana, Buenos Aires, Argentina, 2016. 

  • Kamran N, Calinescu A, Candolfi M, Chandran M, Mineharu Y, Asad AS, Koschmann C, Nunez FJ, Lowenstein PR, Castro MG. Recent advances and future of immunotherapy for glioblastoma. Expert OpinBiolTher. 2016 16:1245-1264.

  • Mitochondrial dynamics regulates oxidative metabolism in Leydig tumor cells” Cecilia Poderoso, Cristina Paz, Katia E. Helfenberger and Ernesto J. Podestá. Capítulo 10: General aspects of oxidative stress. “Biochemistry of oxidative stress. Physiopathology and clinical aspects”. Editores: Gelpi RJ, Boveris A, Poderoso JJ. Editorial: Springer, New York. Serie “Advances in Biochemistry in Health and Disease”. ISBN: 978-3-319-45864-9.(2016). http://www.springer.com/la/book/9783319458649.

  • Kamran N, Candolfi M, Baker GJ, Moreno Ayala MA, Dzaman M, Lowenstein PR, Castro MG. Gene Therapy for the Treatment of Neurological Disorders: Central Nervous System Neoplasms Fredric P. Manfredsson (ed.), Gene Therapy for Neurological Disorders: Methods and Protocols, Methods in Molecular Biology, vol. 1382 (2016), 467-482 Springer Science+Business Media New York

  • Pigozzi MI. The Chromosomes of Birds during Meiosis. Cytogenet Genome Res. 2016; 150(2):128-138. doi: 10.1159/000453541. Review.

  • del Priore L, Pigozzi MI. Meiotic recombination analysis in female ducks (Anas platyrhynchos). Genetica. 2016 ; 144(3):307-12. doi: 10.1007/s10709-016-9899-9.

  • Magri ML, Gottardo MF, Zárate S, Eijo G, Ferraris MJ, Jaita G, Moreno Ayala MA, Candolfi M, Pisera D, Seilicovich A. Opposite effects of dihydrotestosterone and estradiol on apoptosis in the anterior pituitary gland from male rats. Endocrine 2016 51: 506-516.

  • L. Carniglia, D. Ramírez, D. Durand, J. Saba, C. Caruso, M. Lasaga. [Nle4, D-Phe7]-a-MSH inhibits toll-like receptor (TLR)2- and TLR4-induced microglial activation and promotes a M2-like phenotype. PloSone 2016, 11(6):e0158564.

  • Paz C, Cornejo Maciel F, Gorostizaga A, Castillo AF, Mori Sequeiros García MM, Maloberti PM, Orlando UD, Mele PG, Poderoso C, Podesta EJ. Role of Protein Phosphorylation and TyrosinePhosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function. Front Endocrinol (Lausanne). 2016 Jun 9. Review.

  • Gorostizaga AB; Mori Sequeiros García MM; Acquier AB; Lopez-Costa JJ; Mendez CF; Maloberti PM; Paz C. ACTH Modulates PTP-PEST Activity and Promotesits Interaction with Paxillin. Journal of cellular biochemistry; Lugar: New York; Año: 2016 vol. 117 p. 2170 – 2181

  • Spectrum of BRCA1/2 variants in 940 patients from Argentina including novel, deleterious and recurrent germline mutations: impact on health care and clinical practice. Angela Rosaria Solano, Florencia Cecilia Cardoso, Vanesa Romano, Florencia Perazzo, Carlos Bas, Gonzalo Recondo, Francisco Bernardo Santillan, Eduardo Gonzalez, Eduardo Abalo, María Viniegra, José Davalos Michel, Lina María Nuñez, Cristina Maria Noblia, Ignacio Mc Lean, Enrique DiazCanton, Reinaldo Daniel Chacon, Gustavo Cortese, Eduardo Beccar Varela, Martín Greco, María Laura Barrientos, Silvia Adela Avila, Hector Daniel Vuotto, Antonio Lorusso, Ernesto Jorge Podesta and Oscar Gaspar Mando. July 2016 doi: 10.18632/oncotarget.10814

  • "Observación del efecto reductor de N-Acetilcisteína en el metabolismo de levaduras." Journal of Biochemistry Education; San Pablo; 2016. Capela S.P.; Romo Manzini M.; Burgos H.H., Alonso M.; Stella C.A.

2015

2014

2013

2012

Patentes:

  • DESARROLLO DE PRODUCTOS, PROCESOS PRODUCTIVOS Y SISTEMAS TECNOLOGICOS

    Año de referencia: 2017.

    Estado otorgado

    Aprobada en Estados Unidos en Abril del 2017

    Registro: US 9737515 B2

    Denominación del desarrollo: COMPOSITIONS AND METHODS FOR INHIBITING GROWTH OF ACSL4-OVEREXPRESSING TUMORS

    Tipo de desarrollo: Producto

    Breve descripción del desarrollo:

    The present invention relates to compositions and methods for preventing and treating proliferative diseases, such as cancer. More specifically, the present invention relates to compositions and methods for inhibiting tumor growth, particularly breast cancer, in a combined pharmacological treatment. Yet more specifically, the method of the present invention is a method for inhibiting growth of ACSL4-overexpressing tumors. In a preferred embodiment, the invention provides a pharmaceutical composition for inhibiting tumor growth comprising a combination of: i) a first component which is an ACSL4 inhibitor; and ii) a second component selected from a group of chemotherapeutics drugs.

    Áreas de conocimiento: CIENCIAS MÉDICAS Y DE LA SALUD - Medicina Clínica - Oncología

    Autor/es: Podesta, Ernesto J.; Castillo, Ana F.;Orlando, Ulises;Maloberti, Paula;Solano, Angela (INSTITUTO DE INVESTIGACIONES BIOMEDICAS (INBIOMED) ; (CONICET - UBA))

    Inst./es financiadora/s: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)

    Participación: 100 %

    Año de referencia: 2017

    Envió PCT Internacional

 

  • En trámite 3 de Marzo 2017

    Denominación del desarrollo: COMPOSITIONS AND METHODS FOR INHIBITING TUMIOR GROWTH

    Tipo de desarrollo: Producto

    Breve descripción del desarrollo:

    The present invention relates to compositions and methods for preventing and treating cell proliferation in cancer. More specifically, the present invention relates to compositions and methods for inhibiting tumor growth, and for treating proliferative diseases, particularly colon and breast cancer, with a combined pharmacological approach. Yet more specifically, the compositions for inhibiting tumor growth comprise a combination of: i) a first component which is an ACSL4 inhibitor; and ii) a second component selected from the group consisting of mTOR inhibitor and ER inhibitor.

    Áreas de conocimiento: CIENCIAS MÉDICAS Y DE LA SALUD - Medicina Clínica - Oncología

    Campo aplicación: Salud humana Especialidad: Oncología

    Autor/es: Podestá, Ernesto J; Maloberti, Paula;Orlando, Ulises;Dattilo, Melina;Castillo, Ana Fernanda;Solano, Angela (INSTITUTO DE INVESTIGACIONES BIOMEDICAS (INBIOMED) ; (CONICET - UBA))

    Inst./es financiadora/s: CONSEJO NACIONAL DE INVESTIGACIONES

    CIENTIFICAS Y TECNICAS (CONICET)

    Participación: 100 %

     

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