Trabajos Cardiovascular
Effect of lithium in pyramidal neurons of Cornu Ammonis in an animal model. Ossani GP, Riudavets MA, D'Annunzio V, Uceda AM, Ponzo O, Lago NR, Martino DJ. J Psychiatr Res. 2023 Oct 5;167:33-36. doi: 10.1016/j.jpsychires.2023.10.001. Online ahead of print.
Bin EP, Zaobornyj T, Garces M, D'Annunzio V, Buchholz B, Marchini T, Evelson P, Gelpi RJ, Donato M. Remote ischemic preconditioning prevents sarcolemmal-associated proteolysis by MMP-2 inhibition. Mol Cell Biochem. 2023 Sep 20. doi: 10.1007/s11010-023-04849-2. Online ahead of print.
Cevey ÁC, Pieralisi AV, Donato M, Rada J, Gelpi RJ, Mirkin GA, Goren NB, Penas FN. Macrophages Mediate Healing Properties of Fenofibrate in Experimental Chagasic Cardiomyopathy. ACS Infect Dis. 2023 Feb 10;9(2):213-220. doi: 10.1021/acsinfecdis.2c00535. Epub 2023 Jan 20.
Marchini T, Magnani N, Garces M, Kelly J, Paz M, Caceres L, Calabro V, Lasagni Vitar R, Caltana L, Contin M, Reynoso S, Lago N, Vico T, Vanasco V, Wolf D, Tripodi V, Gonzalez Maglio D, Alvarez S, Buchholz B, Berra A, Gelpi R, Evelson P. Chronic exposure to polluted urban air aggravates myocardial infarction by impaired cardiac mitochondrial function and dynamics. Environ Pollut. 2022 Feb 15;295:118677. doi: 10.1016/j.envpol.2021.118677. Epub 2021 Dec 11.
Gelpi RJ. A New Therapeutic Alternative for the Treatment of Pulmonary Hypertension? Arq Bras Cardiol. 2021 Dec;117(6):1113-1114. English, Portuguese. doi: 10.36660/abc.20210935.
Donato M, Bin EP, D Annunzio V, Gelpi RJ. Myocardial remote ischemic preconditioning: from cell biology to clinical application. Mol Cell Biochem. 2021 Oct;476(10):3857-3867. doi:10.1007/s11010-021-04192-4.
Pérez ML, Merino SF, Racca ML, Gelpi RJ, Rancich AM. ¿Enfatizan los juramentos el bienestar y cuidado del médico en pandemia? [Do oaths emphasize The doctors' welfare and care in pandemic?]. Medicina (B Aires). 2021; 81(3):486-487. Spanish.
Chowdhury T, Lemaître F, Golanov E, Kuypers KLAM, Buchholz B, Gelpi RJ, Schaller B. A Step further-The Role of Trigeminocardiac Reflex in Therapeutic Implications: Hypothesis, Evidence, and Experimental Models. J Neurosurg Anesthesiol. 2021 Feb 2. doi:10.1097/ANA.0000000000000760.
Cerrudo CS, Cavallero S, Rodríguez Fermepín M, González GE, Donato M, Kouyoumdzian NM, Gelpi RJ, Hertig CM, Choi MR, Fernández BE. Cardiac Natriuretic Peptide Profiles in Chronic Hypertension by Single or Sequentially Combined Renovascular and DOCA-Salt Treatments. Front Physiol. 2021 May 25;12:651246. doi: 10.3389/fphys.2021.651246.
Parodi JB, de Lima AA, Burgos LM, Gelpi RJ. Validation of a Spanish version of a 360° feedback tool for residents' performance: A pilot study. Educ Health (Abingdon). 2020 Sep-Dec;33(3):95-107. doi: 10.4103/efh.EfH_119_19.
Del Mauro JS, Prince PD, Allo MA, Santander Plantamura Y, Morettón MA, González GE, Bertera FM, Carranza A, Gorzalczany SB, Chiappetta DA, Morales C, Gelpi RJ, Taira CA, Polizio AH, Donato M, Höcht C. Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats. J Hypertens. 2020 Mar;38(3):536-545. doi: 10.1097/HJH.0000000000002284.
Mazo T, D'Annunzio V, Donato M, Perez V, Zaobornyj T, Gelpi RJ. Dyslipidemia in Ischemia/Reperfusion Injury. Adv Exp Med Biol. 2019;1127:117-130. doi: 10.1007/978-3-030-11488-6_8.
Vico TA, Marchini T, Ginart S, Lorenzetti MA, Adán Areán JS, Calabró V, Garcés M, Ferrero MC, Mazo T, D'Annunzio V, Gelpi RJ, Corach D, Evelson P, Vanasco V, Alvarez S. Mitochondrial bioenergetics links inflammation and cardiac contractility in endotoxemia. Basic Res Cardiol. 2019 Aug 19;114(5):38. doi: 10.1007/s00395-019-0745-y.
Paez DT, Garces M, Calabró V, Bin EP, D'Annunzio V, Del Mauro J, Marchini T, Höcht C, Evelson P, Gelpi RJ, Donato M. Adenosine A<sub>1</sub> receptors and mitochondria: targets of remote ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H743-H750. doi: 10.1152/ajpheart.00071.2018.
Sbaraglini ML, Bellera CL, Quarroz Braghini J, Areco Y, Miranda C, Carrillo C, Kelly J, Buchholz B, Gelpi RJ, Talevi A, Alba Soto CD. Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease. Eur J Med Chem. 2019 Dec 15;184:111778. doi: 10.1016/j.ejmech.2019.111778.
Mazo T, D Annunzio V, Zaobornyj T, Perez V, Gomez A, Berg G, Barchuk M, Ossani G, Martinefski M, Tripodi V, Lago N, Gelpi RJ. High-fat diet abolishes the cardioprotective effects of ischemic postconditioning in murine models despite increased thioredoxin-1 levels. Mol Cell Biochem. 2019 Feb;452(1-2):153-166. doi: 10.1007/s11010-018-3421-x.
Zaobornyj T, Mazo T, Perez V, Gomez A, Contin M, Tripodi V, D'Annunzio V, Gelpi RJ. Thioredoxin-1 is required for the cardioprotecive effect of sildenafil against ischaemia/reperfusion injury and mitochondrial dysfunction in mice. Free Radic Res. 2019 Oct;53(9-10):993-1004. doi: 10.1080/10715762.2019.1661404.
Auzmendi J, Buchholz B, Salguero J, Cañellas C, Kelly J, Men P, Zubillaga M, Rossi A, Merelli A, Gelpi RJ, Ramos AJ, Lazarowski A. Pilocarpine-Induced Status Epilepticus Is Associated with P-Glycoprotein Induction in Cardiomyocytes, Electrocardiographic Changes, and Sudden Death. Pharmaceuticals (Basel). 2018 Feb 16;11(1):21. doi: 10.3390/ph11010021.
Buchholz B, Kelly J, Muñoz M, Bernatené EA, Méndez Diodati N, González Maglio DH, Dominici FP, Gelpi RJ. Vagal stimulation mimics preconditioning and postconditioning of ischemic myocardium in mice by activating different protection mechanisms. Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1289-H1297. doi: 10.1152/ajpheart.00286.2017.
Helfenberger KE, Villalba NM, Buchholz B, Boveris A, Poderoso JJ, Gelpi RJ, Poderoso C. Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells. PLoS One. 2018 Feb 28;13(2):e0193022. doi: 10.1371/journal.pone.0193022.
Barchuk M, Miksztowicz V, Zago V, Cevey A, López G, Goren N, Friedman S, Gelpi RJ, Morales C, Fernandez Tomé MDC, Schreier L, Berg G. Endothelial Lipase Is an Alternative Pathway for Fatty Acid Release from Lipoproteins: Evidence from a High Fat Diet Model of Obesity in Rats. Lipids. 2018 Oct;53(10):993-1003. doi: 10.1002/lipd.12107.
Donato M, Evelson P, Gelpi RJ. Protecting the heart from ischemia/reperfusion injury: an update on remote ischemic preconditioning and postconditioning. Curr Opin Cardiol. 2017 Nov;32(6):784-790. doi: 10.1097/HCO.0000000000000447.
Buchholz B, Kelly J, Bernatene EA, Méndez Diodati N, Gelpi RJ. Antagonistic and Synergistic Activation of Cardiovascular Vagal and Sympathetic Motor Outflows in Trigeminal Reflexes. Front Neurol. 2017 Feb 21;8:52. doi: 10.3389/fneur.2017.00052.
Nicolosi LN, Lewin PG, Rudzinski JJ, Pompeo M, Guanca F, Rodríguez P, Gelpi RJ, Rubio MC. Relation between periodontal disease and arterial stiffness. J Periodontal Res. 2017 Feb;52(1):122-126. doi: 10.1111/jre.12376.
Rancich AM, Fernanda-Merino S, Valicenti MC, López-Prieto MB, Donato M, Gelpi RJ. Incidentes moralmente incorrectos percibidos por alumnos de tercer año de Medicina en 2009 y 2015 [Morally incorrect incidents perceived by third year medical students in 2009 and 2015]. Gac Med Mex. 2017 Jan-Feb;153(1):36-43. Spanish.
Bombicino SS, Iglesias DE, Rukavina-Mikusic IA, Buchholz B, Gelpi RJ, Boveris A, Valdez LB. Hydrogen peroxide, nitric oxide and ATP are molecules involved in cardiac mitochondrial biogenesis in Diabetes. Free Radic Biol Med. 2017 Nov;112:267-276. doi: 10.1016/j.freeradbiomed.2017.07.027.
Donato M, Buchholz B, Morales C, Valdez L, Zaobornyj T, Baratta S, Paez DT, Matoso M, Vaccarino G, Chejtman D, Agüero O, Telayna J, Navia J, Hita A, Boveris A, Gelpi RJ. Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy. Mol Cell Biochem. 2017 Aug;432(1-2):169-178. doi: 10.1007/s11010-017-3007-z.
Cevey ÁC, Mirkin GA, Donato M, Rada MJ, Penas FN, Gelpi RJ, Goren NB. Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease. Int J Parasitol Drugs Drug Resist. 2017 Dec;7(3):378-387. doi: 10.1016/j.ijpddr.2017.10.003.
Del Mauro JS, Prince PD, Donato M, Fernandez Machulsky N, Morettón MA, González GE, Bertera FM, Carranza A, Gorzalczany SB, Chiappetta DA, Berg G, Morales C, Gelpi RJ, Taira CA, Höcht C. Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability. J Am Soc Hypertens. 2017 Apr;11(4):227-240. doi: 10.1016/j.jash.2017.02.007.
Sanchez V, Villalba N, Fiore L, Luzzani C, Miriuka S, Boveris A, Gelpi RJ, Brusco A, Poderoso JJ. Characterization of Tunneling Nanotubes in Wharton's jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells. Stem Cell Rev Rep. 2017 Aug;13(4):491-498. doi: 10.1007/s12015-017-9730-8.
Perez V, D Annunzio V, Mazo T, Marchini T, Caceres L, Evelson P, Gelpi RJ. Ischemic postconditioning confers cardioprotection and prevents reduction of Trx-1 in young mice, but not in middle-aged and old mice. Mol Cell Biochem. 2016 Apr;415(1-2):67-76. doi: 10.1007/s11010-016-2677-2.
Gelpi RJ. Cardiovagal activity confers cardioprotection after myocardial infarction: recent advances. Exp Physiol. 2016 May 1;101(5):563-4. doi: 10.1113/EP085329.
D'Annunzio V, Perez V, Boveris A, Gelpi RJ, Poderoso JJ. Role of thioredoxin-1 in ischemic preconditioning, postconditioning and aged ischemic hearts. Pharmacol Res. 2016 Jul;109:24-31. doi: 10.1016/j.phrs.2016.03.009. Epub 2016 Mar 14.
Donato M, Goyeneche MA, Garces M, Marchini T, Pérez V, Del Mauro J, Höcht C, Rodríguez M, Evelson P, Gelpi RJ. Myocardial triggers involved in activation of remote ischaemic preconditioning. Exp Physiol. 2016 Jun 1;101(6):708-16. doi: 10.1113/EP085535. Epub 2016 May 1.
Fernandez Machulsky N, Gagliardi J, Fabre B, Miksztowicz V, Lombardo M, García Escudero A, Gigena G, Blanco F, Gelpi RJ, Schreier L, Gidron Y, Berg G. Matrix metalloproteinases and psychosocial factors in acute coronary syndrome patients. Psychoneuroendocrinology. 2016 Jan;63:102-8. doi: 10.1016/j.psyneuen.2015.09.015.
Bombicino SS, Iglesias DE, Mikusic IAR, D'Annunzio V, Gelpi RJ, Boveris A, Valdez LB. Diabetes impairs heart mitochondrial function without changes in resting cardiac performance. Int J Biochem Cell Biol. 2016 Dec;81(Pt B):335-345. doi: 10.1016/j.biocel.2016.09.018.
Buchholz B, Merino SF, Pérez ML, Gelpi RJ, Rancich AM. Lithotomy's prohibition and referral to experts in medical oaths of hippocratic stemma. Actas Urol Esp. 2016 Dec;40(10):640-645. English, Spanish. doi: 10.1016/j.acuro.2015.12.014.
Sánchez-Villamil JP, D'Annunzio V, Finocchietto P, Holod S, Rebagliati I, Pérez H, Peralta JG, Gelpi RJ, Poderoso JJ, Carreras MC. Cardiac-specific overexpression of thioredoxin 1 attenuates mitochondrial and myocardial dysfunction in septic mice. Int J Biochem Cell Biol. 2016 Dec;81(Pt B):323-334. doi: 10.1016/j.biocel.2016.08.045.
Perez V, D'Annunzio V, Valdez LB, Zaobornyj T, Bombicino S, Mazo T, Carbajosa NL, Gironacci MM, Boveris A, Sadoshima J, Gelpi RJ. Thioredoxin-1 Attenuates Ventricular and Mitochondrial Postischemic Dysfunction in the Stunned Myocardium of Transgenic Mice. Antioxid Redox Signal. 2016 Jul 10;25(2):78-88. doi: 10.1089/ars.2015.6459.
D Annunzio V, Perez V, Mazo T, Muñoz MC, Dominici FP, Carreras MC, Poderoso JJ, Sadoshima J, Gelpi RJ. Loss of myocardial protection against myocardial infarction in middle-aged transgenic mice overexpressing cardiac thioredoxin-1. Oncotarget. 2016 Mar 15;7(11):11889-98. doi: 10.18632/oncotarget.7726.
Gagliardi JA, Maciel N, Castellano JL, Masoli O, Miksztowicz V, Berg G, Bermejo E, Lazzari M, Gelpi RJ. Relationship between endothelial progenitor cells and vascular endothelial growth factor and its variation with exercise. Thromb Res. 2016 Jan;137:92-96. doi:10.1016/j.thromres.2015.11.012.
González GE, Wilensky L, Cassaglia P, Morales C, Gelpi RJ. Early administration of Enalapril prevents diastolic dysfunction and ventricular remodeling in rabbits with myocardial infarction. Cardiovasc Pathol. 2016 May- Jun;25(3):208-213. doi: 10.1016/j.carpath.2016.01.004.
Perez V, D Annunzio V, Mazo T, Marchini T, Caceres L, Evelson P, Gelpi RJ. Inhibition of endogenous thioredoxin-1 in the heart of transgenic mice does not confer cardioprotection in ischemic postconditioning. Int J Biochem Cell Biol. 2016 Dec;81(Pt B):315-322. doi: 10.1016/j.biocel.2016.09.017.
Buchholz B, Donato M, Perez V, Deutsch ACR, Höcht C, Del Mauro JS, Rodríguez M, Gelpi RJ. Changes in the loading conditions induced by vagal stimulation modify the myocardial infarct size through sympathetic-parasympathetic interactions. Pflugers Arch. 2015 Jul;467(7):1509-1522. doi: 10.1007/s00424-014-1591-2.
Marchini T, D'Annunzio V, Paz ML, Cáceres L, Garcés M, Perez V, Tasat D, Vanasco V, Magnani N, Gonzalez Maglio D, Gelpi RJ, Alvarez S, Evelson P. Selective TNF-α targeting with infliximab attenuates impaired oxygen metabolism and contractile function induced by an acute exposure to air particulate matter. Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1621-8. doi: 10.1152/ajpheart.00359.2015.
Hita A, Baratta S, Vaccarino G, Navia J, Oleno D, Telayna JM, Costantini R, Chejtman D, Matoso M, Gelpi RJ, Donato M, Morales C. Severe aortic stenosis with preserved ejection fraction and evidence of impairment in structure, myocardial strain and ventricular function: A new contribution to clinical decision making. Cardiol J. 2015;22(6):613-21. doi: 10.5603/CJ.a2015.0034.
Buchholz B, Donato M, D'Annunzio V, Gelpi RJ. Ischemic postconditioning: mechanisms, comorbidities, and clinical application. Mol Cell Biochem. 2014 Jul;392(1-2):1-12. doi:10.1007/s11010-014-2014-6. Epub 2014 Mar 13.
Buchholz B, D Annunzio V, Giani JF, Siachoque N, Dominici FP, Turyn D, Perez V, Donato M, Gelpi RJ. Ischemic postconditioning reduces infarct size through the α1-adrenergic receptor pathway. J Cardiovasc Pharmacol. 2014 Jun;63(6):504-11. doi: 10.1097/FJC.0000000000000074.
Buchholz B, Perez V, Siachoque N, Miksztowicz V, Berg G, Rodríguez M, Donato M, Gelpi RJ. Dystrophin proteolysis: a potential target for MMP-2 and its prevention by ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2014 Jul 1;307(1):H88-96. doi: 10.1152/ajpheart.00242.2013.
González GE, Cassaglia P, Noli Truant S, Fernández MM, Wilensky L, Volberg V, Malchiodi EL, Morales C, Gelpi RJ. Galectin-3 is essential for early wound healing and ventricular remodeling after myocardial infarction in mice. Int J Cardiol. 2014 Oct 20;176(3):1423-5. doi: 10.1016/j.ijcard.2014.08.011.
Seropian IM, Cerliani JP, Toldo S, Van Tassell BW, Ilarregui JM, González GE, Matoso M, Salloum FN, Melchior R, Gelpi RJ, Stupirski JC, Benatar A, Gómez KA, Morales C, Abbate A, Rabinovich GA. Galectin-1 controls cardiac inflammation and ventricular remodeling during acute myocardial infarction. Am J Pathol. 2013 Jan;182(1):29-40. doi: 10.1016/j.ajpath.2012.09.022.
Donato M, Buchholz B, Rodríguez M, Pérez V, Inserte J, García-Dorado D, Gelpi RJ. Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning. Exp Physiol. 2013 Feb;98(2):425-34. doi: 10.1113/expphysiol.2012.066217.
Marchini T, Magnani N, D'Annunzio V, Tasat D, Gelpi RJ, Alvarez S, Evelson P. Impaired cardiac mitochondrial function and contractile reserve following an acute exposure to environmental particulate matter. Biochim Biophys Acta. 2013 Mar;1830(3):2545-52. doi: 10.1016/j.bbagen.2012.11.012.
Donato M, Gelpi RJ. Assessment of longitudinal myocardial stiffness is not enough to evaluate diastolic function: what is the relevance of the stiffness of cardiomyocytes in the transverse direction? Circ J. 2013;77(3):608-9. doi: 10.1253/circj.cj-13-0061.
D'Annunzio V, Donato M, Buchholz B, Pérez V, Miksztowicz V, Berg G, Gelpi RJ. High cholesterol diet effects on ischemia-reperfusion injury of the heart. Can J Physiol Pharmacol. 2012 Sep;90(9):1185-96. doi: 10.1139/y2012-085.
D'Annunzio V, Donato M, Fellet A, Buchholz B, Antico Arciuch VG, Carreras MC, Valdez LB, Zaobornyj T, Morales C, Boveris A, Poderoso JJ, Balaszczuk AM, Gelpi RJ. Diastolic function during hemorrhagic shock in rabbits. Mol Cell Biochem. 2012 Jan;359(1-2):169-76. doi: 10.1007/s11010-011-1011-2.
Buchholz B, Donato M, Perez V, Ivalde FC, Höcht C, Buitrago E, Rodríguez M, Gelpi RJ. Preischemic efferent vagal stimulation increases the size of myocardial infarction in rabbits. Role of the sympathetic nervous system. Int J Cardiol. 2012 Mar 22;155(3):490-1. doi: 10.1016/j.ijcard.2011.12.082.
Valdez LB, Zaobornyj T, Bombicino S, Iglesias DE, Boveris A, Donato M, D'Annunzio V, Buchholz B, Gelpi RJ. Complex I syndrome in myocardial stunning and the effect of adenosine. Free Radic Biol Med. 2011 Sep 15;51(6):1203-12. doi: 10.1016/j.freeradbiomed.2011.06.007.
Gelpi RJ, Park M, Gao S, Dhar S, Vatner DE, Vatner SF. Apoptosis in severe, compensated pressure overload predominates in nonmyocytes and is related to the hypertrophy but not function. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H1062-8. doi: 10.1152/ajpheart.00998.2010. Epub 2010 Dec 10.
Donato M, D'Annunzio V, Buchholz B, Miksztowicz V, Carrión CL, Valdez LB, Zaobornyj T, Schreier L, Wikinski R, Boveris A, Berg G, Gelpi RJ. Role of matrix metalloproteinase-2 in the cardioprotective effect of ischaemic postconditioning. Exp Physiol. 2010 Feb;95(2):274-81. doi: 10.1113/expphysiol.2009.049874.
Cavallero S, González GE, Seropian IM, Cerrudo CS, Matorra F, Morales C, Hertig CM, Puyó AM, Fernández BE, Gelpi RJ. Ventricular function and natriuretic peptides in sequentially combined models of hypertension. Am J Physiol Heart Circ Physiol. 2010 Apr;298(4):H1290-9. doi: 10.1152/ajpheart.00911.2009.
Gelpi RJ, Gao S, Zhai P, Yan L, Hong C, Danridge LM, Ge H, Maejima Y, Donato M, Yokota M, Molkentin JD, Vatner DE, Vatner SF, Sadoshima J. Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload. Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1814-9. doi: 10.1152/ajpheart.00449.2009.
Gonzalez GE, Rabald S, Briest W, Gelpi RJ, Seropian I, Zimmer HG, Deten A. Ribose treatment reduced the infarct size and improved heart function after myocardial infarction in rats. Cell Physiol Biochem. 2009;24(3-4):211-8. doi: 10.1159/000233247.
González GE, Seropian IM, Krieger ML, Palleiro J, Lopez Verrilli MA, Gironacci MM, Cavallero S, Wilensky L, Tomasi VH, Gelpi RJ, Morales C. Effect of early versus late AT(1) receptor blockade with losartan on postmyocardial infarction ventricular remodeling in rabbits. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H375-86. doi: 10.1152/ajpheart.00498.2007.
D'Annunzio V, Donato M, Erni L, Miksztowicz V, Buchholz B, Carrión CL, Schreier L, Wikinski R, Gelpi RJ, Berg G, Basso N. Rosuvastatin given during reperfusion decreases infarct size and inhibits matrix metalloproteinase-2 activity in normocholesterolemic and hypercholesterolemic rabbits. J Cardiovasc Pharmacol. 2009 Feb;53(2):137-44. doi: 10.1097/FJC.0b013e318197c5e9.
Berrocal DH, González GE, Fernández A, Perez S, Wilensky L, Morales C, Grinfeld L, Gelpi RJ. Effects of overexpansion on stents' recoil, symmetry/asymmetry, and neointimal hyperplasia in aortas of hypercholesterolemic rabbits. Cardiovasc Pathol. 2008 Sep-Oct;17(5):289-96. doi: 10.1016/j.carpath.2007.10.005.
Abbate A, De Falco M, Morales C, Gelpi RJ, Prisco M, De Luca A, Palleiro J, Fedele V, Feroce F, Baldi F, Vetrovec GW, Baldi A. Electron microscopy characterization of cardiomyocyte apoptosis in ischemic heart disease. Int J Cardiol. 2007 Jan 2;114(1):118-20. doi: 10.1016/j.ijcard.2005.11.025.
Abbate A, Morales C, De Falco M, Fedele V, Biondi Zoccai GG, Santini D, Palleiro J, Vasaturo F, Scarpa S, Liuzzo G, Severino A, Baldi F, Crea F, Biasucci LM, Vetrovec GW, Gelpi RJ, Baldi A. Ischemia and apoptosis in an animal model of permanent infarct-related artery occlusion. Int J Cardiol. 2007 Sep 14;121(1):109-11. doi: 10.1016/j.ijcard.2006.08.077.
Cavallero S, González GE, Puyó AM, Rosón MI, Pérez S, Morales C, Hertig CM, Gelpi RJ, Fernández BE. Atrial natriuretic peptide behaviour and myocyte hypertrophic profile in combined pressure and volume-induced cardiac hypertrophy. J Hypertens. 2007 Sep;25(9):1940-50. doi: 10.1097/HJH.0b013e3282435b1e. PMID: 17762660.
Donato M, D'Annunzio V, Berg G, Gonzalez G, Schreier L, Morales C, Wikinski RL, Gelpi RJ. Ischemic postconditioning reduces infarct size by activation of A1 receptors and K+(ATP) channels in both normal and hypercholesterolemic rabbits. J Cardiovasc Pharmacol. 2007 May;49(5):287-92. doi: 10.1097/FJC.0b013e31803c55fe.
Pérez SG, Gelpi RJ, Rancich AM. Doctor-patient sexual relationships in medical oaths. J Med Ethics. 2006 Dec;32(12):702-5. doi: 10.1136/jme.2005.014910.
Berrocal DH, González GE, Morales C, Gelpi RJ, Grinfeld LR. Irinotecan- eluting stents inhibited neointimal proliferation in hypercholesterolemic rabbit aortas. Catheter Cardiovasc Interv. 2006 Jul;68(1):89-96. doi: 10.1002/ccd.20694.
Pascua A, Donato M, Borrego C, Gabay J, Berrocal D, Gelpi RJ, Grinfeld L. Evaluación de la función diastólica durante y post-ejercicio isométrico en pacientes con hipertensión arterial [Evaluation of diastolic function during and post-exercise in patients with arterial hypertension]. Medicina (B Aires). 2006;66(5):433-8. Spanish.
González GE, Rodríguez M, Donato M, Palleiro J, D'Annunzio V, Morales C, Gelpi RJ. Effects of low-calcium reperfusion and adenosine on diastolic behavior during the transitory systolic overshoot of the stunned myocardium in the rabbit. Can J Physiol Pharmacol. 2006 Feb;84(2):265-72. doi: 10.1139/Y05-122.
Rancich AM, Pérez ML, Morales C, Gelpi RJ. Beneficence, justice, and lifelong learning expressed in medical oaths. J Contin Educ Health Prof. 2005 Summer;25(3):211-20. doi: 10.1002/chp.32.
Gabay J, Donato M, Pascua A, Gelpi RJ, Grinfeld L. Effects of isometric exercise on the diastolic function in patients with severe aortic stenosis with or without coronary lesion. Int J Cardiol. 2005 Sep 15;104(1):52-8. doi: 10.1016/j.ijcard.2004.10.014.
González GE, Palleiro J, Monroy S, Pérez S, Rodríguez M, Masucci A, Gelpi RJ, Morales C. Effects of the early administration of losartan on the functional and morphological aspects of postmyocardial infarction ventricular remodeling in rabbits. Cardiovasc Pathol. 2005 Mar-Apr;14(2):88-95. doi: 10.1016/j.carpath.2004.12.003.
D'Annunzio V, Donato M, Sabán M, Sanguinetti SM, Wikinski RL, Gelpi RJ. Hypercholesterolemia attenuates postischemic ventricular dysfunction in the isolated rabbit heart. Mol Cell Biochem. 2005 May;273(1-2):137-43. doi: 10.1007/s11010-005-8264-6.
González GE, Mangas F, Palleiro J, Rodríguez M, Depetris Chauvin A, Gelpi RJ, Morales C. Efectos de la administración temprana de losartán sobre el remodelamiento ventricular en conejos con infarto de miocardio experimental [Effects of the early administration of losartan on ventricular remodeling in rabbits with experimental myocardial infarction]. Medicina (B Aires). 2004;64(1):25-9. Spanish.
Donato M, Gelpi RJ. Adenosine and cardioprotection during reperfusion—an overview. Mol Cell Biochem. 2003 Sep;251(1-2):153-9.
Ruiz GA, Calvar C, Hermes R, Rivadeneira D, Bengolea V, Chirife R, Tentori MC, Gelpi RJ. Insulin sensitivity in young women with vasovagal syncope. Am Heart J. 2003 May;145(5):834-40. doi: 10.1016/S0002-8703(02)94707-1.
Pérez ML, Gelpi RJ, Rancich AM. Discriminación en la atención médica: una mirada a través de los juramentos médicos [Discrimination in medical assistance: An overview based on medical oath]. Rev Med Chil. 2003 Jul;131(7):799-807. Spanish.
González GE, Mangas F, Chauvin AD, Monroy S, Donato M, Morales C, Gelpi RJ. Comportamiento diastólico durante la fase de "hipercontracción" postisquémica en el miocardio atontado de conejo [Diastolic behavior during postischemic hypercontraction phase in rabbit stunned myocardium]. Medicina (B Aires). 2003;63(5):403-9. Spanish.
Donato M, Gabay J, Pascua A, Sabán M, Sabarrós J, Gelpi RJ, Grinfeld L. Efectos del ejercicio isométrico sobre la funcion diastólica en pacientes con estenosis aórtica severa [Effects of isometric exercise on the diastolic function in patients with severe aortic stenosis]. Medicina (B Aires). 2003;63(1):33-6. Spanish
Morales C, González GE, Rodríguez M, Bertolasi CA, Gelpi RJ. Histopathologic time course of myocardial infarct in rabbit hearts. Cardiovasc Pathol. 2002 Nov- Dec;11(6):339-45. doi: 10.1016/s1054-8807(02)00115-1.
Gelpi RJ, Morales C, Cohen MV, Downey JM. Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning. Basic Res Cardiol. 2002 Jan;97(1):40-6. doi: 10.1007/s395-002-8386-0.
Donato M, Morales C, D'Annunzio V, Scapín O, Gelpi RJ. La activación de los receptores A1 de adenosina atenúa el atontamiento de miocardio en el conejo [The activation of A1 adenosine receptors attenuates myocardial stunning in the rabbit]. Medicina (B Aires). 2001;61(4):424-30. Spanish.
Morales C, Rodríguez M, González GE, Matoso M, Bertolasi CA, Gelpi RJ. Cronodinamia del infarto de miocardio en el conejo [Time course of the myocardial infarction in the rabbit]. Medicina (B Aires). 2001;61(6):830-6. Spanish.
Donato M, Morales C, Bagnarelli A, Scapín O, Gelpi RJ. Adenosina exógena y disfunción postisquémica en el corazon aislado de conejo [Exogenous adenosine and postischemic dysfunction in the isolated rabbit heart]. Medicina (B Aires). 1999;59(4):339-47. Spanish.
Gelpi RJ, Morales C, Rodríguez M, Bagnarelli A, Hita A, Scapín O. Efecto del enalaprilato sobre la disfunción postisquémica sistólica y diastólica ("miocardio atontado") en el corazón aislado de conejo [Effect of enalaprilat on postischemic systolic and diastolic dysfunction (stunned myocardium) on the isolated rabbit heart]. Medicina (B Aires). 1998;58(1):22-8. Spanish.
Morales C, Rodríguez M, Scapín O, Gelpi RJ. Comparison of the effects of ACE inhibition with those of angiotensin II receptor antagonism on systolic and diastolic myocardial stunning in isolated rabbit heart. Mol Cell Biochem. 1998 Sep;186(1-2):117-21.
